Whether you call it "rise and run", slope, velocity, it all means the rate of change. Which for a line is constant and it is mathematically:
m=(y2-y1)/(x2-x1), in this case:
m=(-1-4)/(2--2)
m=-5/4 or if you prefer
m=-1.25
Which means that your rise and run is -1.25 to 1.
For every increase in run by one unit, the rise, or height, decreases by 1.25 units.
