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Besides detoxification of drugs such as acetaminophen, the liver is involved in and regulates several different biochemical pathways. Which of the following is NOT a biochemical activity of the liver?

A) Regulation of carbohydrate metabolism such as glycogenolysis, glycogenesis, and gluconeogenesis
B) Production of lipases and bile for fat digestion
C) Deamination of amino acid and conversion of the resulting ammonia to urea
D) Lipid metabolism, including cholesterol and lipoprotein synthesis

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Answer:

A) Regulation ofcarbohydrates metabolism such as glycogenolysis, glycogenesis and gluconeogenesis.

Explanation:

Carbohydrate metabolism is regulated by hormones secreted by the pancrease, insulin and glucagon. When insulin is secreted, it causes low blood glucose by stimulating cells, to absorb it for storage (glycogenesis and fat metabolism). This results in protein, glycogen and fat synthesis.

So the liver is regulated by and responds to hormonal stimulus for some metabolic reactions to take place.

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